Table 3.
Mutagenic effect of MeOHL extract from M. arvensis in Salmonella typhimurium TA104 assay system in the presence and absence of exogenous metabolic activation system (S9).
| Extract | Dose µg/plate |
Number of revertants/plate
|
Number of revertants/plate
|
|---|---|---|---|
| -S9 | +S9 | ||
| MeOHL extract | 100 | 415±15 | 497±7 |
| 250 | 500±11 | 525±0 | |
| 500 | 479±1 | 647±1 | |
| SR | - | 477±12 | 744±18 |
| PC(MMS) | 0.65 | 3400±31* | - |
| PC (2-AA) | 5 | - | 2130±23* |
Positive control (PC); methyl-methane-sulfonate (MMS) (0.65 µg/plate); 2-aminoanthracene (2-AA) (5 µg/plate); SR: Spontaneous revertants; MeOHL (Methanol leaf extract).
(*)
p < 0.05 means a significant difference between the revertants of negative control (SR) and the revertants of MeOHL extract.