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. 2018 Apr 1;34(3):260–273. doi: 10.1089/jop.2017.0059

Table 1.

RGFP966 is an HDAC3 Selective Inhibitor

Inhibitor Molar mass Blood–brain barrier permeable? HDAC1 HDAC2 HDAC3
RGFP966 362.4 g/mol Yes IC50 2.069 μM = 1.97 nmol/g retinal tissue IC50 3.961 μM = 3.77 nmol/g retinal tissue IC50 0.064 μM = 0.061 nmol/g retinal tissue