Table 18:

Adverse Effects Reported in a Study Comparing MRgFUS Thalamotomy With Unilateral and Bilateral Deep Brain Stimulation

Adverse Effect	MRgFUS (N = 15), n transient (n at 12 mo)	Bilateral DBS (N = 57), n transient (n at 12 mo)	Unilateral DBS (N = 13), n transient (n at 12 mo)
Procedural Events
Vertigo	11 (0)	0 (0)	0 (0)
Headache	9 (0)	0 (0)	0 (0)
Nausea or vomiting	8 (0)	0 (0)	0 (0)
Warm or flushed feeling	4 (0)	0 (0)	0 (0)
Stereotactic frame pin-site burn	2 (0)	0 (0)	0 (0)
Side Effects
Paresthesia (any)	14 (3)	2 (1)	1 (2)
Gait instability	5 (0)	10 (0)	11 (0)
Dysarthria	1 (0)	10 (6)	1 (0)
Weakness	1 (0)	4 (1)	1 (0)
Dysphagia	0 (0)	2 (0)	0 (0)
Mental status change	0 (0)	3 (3)	1 (0)
Complications
DBS hardware infection	NA	0 (1)	0 (0)
DBS lead erosion	NA	1 (2)	0 (0)
Hemorrhage	0 (0)	2 (0)	0 (0)

Abbreviations: DBS, deep brain stimulation; MRgFUS, magnetic resonance-guided focused ultrasound; N, number of participants in the group; n, number of events reported.

Source: Adapted from Huss et al, 2015.⁴⁰