Table 20:
GRADE Evidence Profile for the Comparison of MRgFUS Thalamotomy, Deep Brain Stimulation, and Radiofrequency Thalamotomy
| Number of Studies (Design) | Risk of Bias | Inconsistency | Indirectness | Imprecision | Publication Bias | Upgrade Considerations | Quality |
|---|---|---|---|---|---|---|---|
| Treatment-Related Complication Rate | |||||||
| 1 (Observational)46 | Serious limitations (−1)a | No serious limitationsb | No serious limitations | No serious limitations | Undetectedb | NA | ⊕ Very Low |
Abbreviations: MRgFUS, magnetic resonance-guided focused ultrasound; NA, not applicable.
a
Risk of bias was highest owing to retrospective data collection methods. The full risk-of-bias assessment is presented in Appendix 2, Table A2.
b
Cannot definitively assess presence or absence because the evidence is derived from a single study.