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Summary of KD for aromatic protons calculated using a STD-NMR build up curve. The STD build-up curve for each proton was plotted and fit to equation 2. STD- AF0 was calculated using equation 3 at each saturation time and plotted vs. ligand concentration and fit to equation 4.
| Proton | KD μM |
|---|---|
| Ha | 324 +/− 146 |
| Hb | 398 +/− 142 |
| Hc | 372 +/− 118 |
| Hd | 398 +/− 114 |
