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. Author manuscript; available in PMC: 2018 May 22.
Published in final edited form as: Dev Cell. 2015 Oct 12;35(1):131–142. doi: 10.1016/j.devcel.2015.09.006

Figure 1. Overview of polarization in the C. elegans zygote.

Figure 1

(A) Overview of key events that occur during polarity establishment and maintenance phases. (B) Distributions of the key polarity proteins at the end of establishment phase (PC) and during maintenance phase at nuclear envelope breakdown (NEBD). Light green dots represent clusters of PAR-3, PAR-6, and PKC-3 that co-localize at the cortex. Magenta dots represent clusters of CHIN-1 that appear during maintenance phase. Note the biphasic localization of active CDC-42 to the posterior during establishment phase and to the anterior during maintenance phase. In this and all subsequent figures, embryos are approximately 50µm in length, and posterior is to the right.