Table 4.
Different characteristics between women tested found to have deleterious mutations and women tested without deleterious mutations
| Characteristics |
BRCA1/2 mutations (n = 15) N (%) |
Genetic testing and no deleterious mutation (n = 105) N (%) |
p valuea |
|---|---|---|---|
| Age at diagnosis | |||
| Mean | 40.9 | 47.5 | 0.03 |
| Significant family historyb | 11 (73.3) | 43 (41.0) | 0.02 |
| TNBC | 6 (40.0) | 20 (19.0) | 0.03 |
| Hormone receptor positive | 5 (25.0) | 67 (63.8) | 0.06 |
a
Comparing women tested with mutations to women tested and without a deleterious mutation
b
Defined as the presence of at least one FDR or SDR affected with breast cancer diagnosed before age 50 or with ovarian cancer at any age