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. Author manuscript; available in PMC: 2018 May 22.
Published in final edited form as: Cell Rep. 2018 Apr 24;23(4):1166–1177. doi: 10.1016/j.celrep.2018.03.124

Figure 4. Cell-Cycle-Related Genes Are Potential SETDB2 Downstream Targets.

Figure 4

(A) Western blot shows H3K9me3 levels in the indicated cells before and after SETDB2 knockdown.

(B and C) H3K9me3 levels as shown for genome-wide H3K9me3 ChIP-seq on SETDB2 knockdown or control cells. Number of mapped reads (B) and density heat map (C) are shown.

(D) GSEA plots are shown for indicated gene sets in SETDB2 knockdown versus control cells.

(E) H3K9me3 ChIP-seq profiles of a subset of potential SETDB2 target genes (n = 27) are shown for SETDB2 knockdown and control cells.

(F) Schematic illustration shows ChIP-seq peaks in CDKN2C locus.

See also Figure S5.