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Pharmacodynamics: % inhibition of HIV, Mean (Standard Deviation)
| Vaginal use phase | Rectal use phase | |||||
|---|---|---|---|---|---|---|
| Pre- dose |
Post- dose |
% change, post- versus pre- dosing |
Pre- dose |
Post- dose |
% change, | |
| post- versus pre-dosing | ||||||
| Cervical vaginal lavage fluid, 1:4 dilution | 41 (14) | 71 (29) | 42% | 39 (16) | 42 (18) | 7% |
| Rectal fluid (sponge), 1:37.5 dilution | 51 (39) | 59 (29) | 14% | 50 (38) | 43 (50) | −14% |
