Figure 1.
Target accumulation of Pan-IR700 in A431 and H520 cells in vitro and in vivo. (A) A flow cytometry analysis for Pan-IR700 affinity for A431 (top) and H520 (bottom) cells (black line: untreated, red line: Pan-IR700-treated). (B) Nude mice implanted with H520 tumors (left) and A431 tumors (right) in the right hind leg were injected with Pan-IR700 24 h prior to fluorescence imaging. Both mice were imaged in the same frame and fluorescence and X-ray modes were simply co-registered.
