Table 1.
The summary of clinical experience.
| # | Protocol | Transient chimerism | Engraftment syndrome | Outcome | I.S. free graft survival |
|---|---|---|---|---|---|
| 1 | NKD03 | + | − | No rejection | > 13 years |
| 2 | NKD03 | + | + | MPGN recurrence | 7 years |
| 3 | NKD03 | + | + | AHR on day 10 (Pre-sensitized) | – |
| 4 | Mod NKD03 | + | + | Chronic rejection after 5 years | 4 years |
| 5 | Mod NKD03 | + | + | Chronic rejection after 7 years | 6 years |
| 6 | ITN036 | + | + | No rejection | > 7.2 years |
| 7 | ITN036 | + | + | No rejection | > 7 years |
| 8 | ITN036 | + | + | Lost graft 6 month due to TMA | – |
| 9 | ITN036 | + | + | No rejection | > 6.8 years |
| 10 | ITN036 | + | + | Acute rejection | 2 months |
| 11 | TBI/aCD2 | + | − | No rejection | > 2.5 years |
| 12 | TBI/aCD2 | − | − | Stable under I.S. | Under I.S. |
I.S.:immunosuppression, TBI: Total Body Irradiation.