Table 1.
Baseline characteristics of the study participants by baseline statin use and hscrp strata, the Multi-Ethnic Study of Atherosclerosis (MESA).
| Non-Users of Statins at Baseline (N = 5,755) | Users of Statins at Baseline (N = 1,002) | |||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| HsCRP (mg/L) | < 1 (N = 1,682) | 1 – 2.99 (N = 1,947) | ≥ 3 (N = 2,126) | P Value | < 1 (N = 340) | 1 – 2.99 (N = 343) | ≥ 3 (N = 319) | P Value |
| Age, years | 59 (51, 69) | 62 (53, 70) | 61 (53, 69) | <0.001 | 67 (59, 73) | 67 (60, 72) | 66 (59, 71) | 0.373 |
| Women | 712 (42.3) | 947 (48.6) | 1,376 (64.7) | <0.001 | 140 (41.2) | 169 (49.3) | 223 (69.9) | <0.001 |
| Race/ethnicity | ||||||||
| Non-Hispanic White | 681 (40.5) | 733 (37.7) | 755 (35.5) | <0.001 | 146 (42.9) | 163 (47.5) | 124 (38.9) | <0.001 |
| African American | 352 (20.9) | 508 (26.1) | 717 (33.7) | 77 (22.7) | 95 (27.7) | 116 (36.4) | ||
| Hispanic | 272 (16.2) | 471 (24.2) | 568 (26.7) | 51 (15.0) | 61 (17.8) | 66 (20.7) | ||
| Chinese American | 377 (22.4) | 235 (12.1) | 86 (4.1) | 66 (19.4) | 24 (7.0) | 13 (4.1) | ||
| Education | ||||||||
| Less than college | 502 (29.9) | 710 (36.6) | 846 (40.0) | <0.001 | 116 (34.2) | 130 (37.9) | 136 (42.6) | 0.049 |
| Technical school certificate, assoc. degree | 791 (47.1) | 900 (46.4) | 968 (45.8) | 144 (42.5) | 142 (41.4) | 136 (42.6) | ||
| Bachelor's degree, graduate or prof. school | 386 (23.0) | 329 (17.0) | 301 (14.2) | 79 (23.3) | 71 (20.7) | 47 (14.7) | ||
| Waist circumference, cm | 90 (83, 98) | 97 (89, 105) | 102 (93, 113) | <0.001 | 95 (87, 102) | 100 (94, 109) | 105 (96, 115) | <0.001 |
| Family history of CHD | 578 (36.7) | 750 (41.1) | 881 (44.3) | <0.001 | 169 (51.7) | 168 (51.4) | 158 (52.8) | 0.929 |
| Current smoker | 185 (11.0) | 233 (12.0) | 360 (17.0) | <0.001 | 20 (5.9) | 32 (9.3) | 45 (14.1) | 0.006 |
| Diabetes | 124 (7.4) | 211 (10.8) | 296 (14.0) | <0.001 | 72 (21.2) | 65 (19.0) | 83 (26.0) | 0.082 |
| SBP, mmHg | 122 (21) | 126 (21) | 129 (22) | <0.001 | 127 (22) | 130 (21) | 133 (22) | 0.004 |
| Medications for hypertension | 373 (22.2) | 542 (27.8) | 777 (36.6) | <0.001 | 164 (48.2) | 190 (55.4) | 198 (62.1) | 0.002 |
| Total cholesterol, mg/dL | 192 (32) | 199 (36) | 197 (37) | <0.001 | 177 (30) | 182 (32) | 186 (38) | 0.003 |
| HDL cholesterol, mg/dL | 50 (41, 61) | 48 (40, 59) | 48 (40, 58) | <0.001 | 51 (43, 60) | 46 (40, 56) | 49 (42, 57) | 0.002 |
| Aspirin use at baseline | 272 (16.9) | 337 (18.1) | 336 (16.4) | 0.393 | 123 (38.3) | 111 (33.8) | 104 (34.0) | 0.404 |
Data presented as mean (SD), median (IQR) or N (%). Percentages may not sum 100% due to rounding
Abbreviations: CHD = coronary heart disease; HDL = high density lipoprotein; HsCRP = high sensitivity C-reactive protein; SBP = systolic blood pressure.