Table 3. Comparison of expression levels of both In-silico and In-vitro analysis related to IGF-1R associated un-treated and treated signaling proteins.

The triple positive sign (+++) indicates the most active, double positive (++) indicates the moderately active and triple negative (---) indicates the down-regulate expression levels of entities in breast cancer cells.

Proteins	Un-treated		Treated
	In-silico simulations	In-vitro western analysis	In-silico simulations	In-vitro western analysis
IGF-1R	+++	++	---	---
IRS-1	+++	+++	---	---
ER-α	++	+++	---	---