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. 2018 May 22;13(5):e0197145. doi: 10.1371/journal.pone.0197145

Table 3. Mortality rate stratified by socio-demographic and clinical characteristics of TB/HIV co-infected children at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, from February 2005 to March 2017.

Characteristics Total N (%) PY Death N (%) IDR
Age (years) <1 11(4.06) 56.10 5(1.85) 8.92
> = 1 260(95.94) 1105.20 33(12.18) 2.99
Residence Urban 219(80.81) 1015.25 28(10.33) 2.76
Rural 52(19.19) 152.40 10(3.69) 6.56
Child lives with Parents 247(91.14) 1094.58 34(12.55) 3.10
Orphaned 11(4.06) 36.00 2(0.74) 5.56
Others 13(4.80) 37.10 2(0.74) 5.40
Baseline WHO stage I & II 34(12.55) 114.25 3(1.11) 2.63
III & IV 237(87.45) 1047.00 35(12.9) 3.34
Baseline immunity status Non-significant/Mild 87(32.10) 337.83 8(2.95) 2.37
Advanced/ severe 184(67.90) 823.42 30(11.07) 3.64
Initial ART regiment based on NRTIs ABC-based 10(3.69) 20.17 5(1.85) 24.81
AZT-based 185(68.27) 828.33 20(7.38) 2.40
D4T-based 67(24.72) 298.17 12(4.43) 4.00
TDF-based 9(3.32) 20.99 1(0.37) 4.81
Treatment failure Yes 28(10.33) 149.58 5(1.85) 3.34
No 243(89.67) 1018.10 33(12.18) 3.24
Clinical failure Yes 5(1.85) 12.67 3(1.11) 23.70
No 266(98.15) 1155.00 35(12.92) 3.00
Isoniazid Yes 97(35.79) 542.00 6(2.21) 1.11
No 174(64.21) 625.66 32(11.81) 5.11
Hemoglobin g/dl <10 48(17.71) 167.58 14(5.17) 8.41
> = 10 223(82.29) 1000.10 24(8.86) 2.40
CPT Yes 236(87.08) 1079.58 28(10.33) 2.60
No 35(12.92) 88.10 10(3.69) 11.40
Adherence Good 231(85.24) 1037.92 23(8.49) 2.22
Fair/poor 40(14.76) 123.33 15(5.54) 12.20
Site of TB PTB 186(68.63) 801.67 13(4.80) 1.62
EPTB 85(31.37) 365.999 25(9.23) 6.83
Follow-up years <1 44(16.24) 15.33 23(8.49) 150.00
1–5 116(42.8) 345.92 9(3.32) 2.60
>5 111(40.96) 800.00 6(2.21) 0.75