Table 3. Mortality rate stratified by socio-demographic and clinical characteristics of TB/HIV co-infected children at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, from February 2005 to March 2017.
Characteristics | Total N (%) | PY | Death N (%) | IDR | |
---|---|---|---|---|---|
Age (years) | <1 | 11(4.06) | 56.10 | 5(1.85) | 8.92 |
> = 1 | 260(95.94) | 1105.20 | 33(12.18) | 2.99 | |
Residence | Urban | 219(80.81) | 1015.25 | 28(10.33) | 2.76 |
Rural | 52(19.19) | 152.40 | 10(3.69) | 6.56 | |
Child lives with | Parents | 247(91.14) | 1094.58 | 34(12.55) | 3.10 |
Orphaned | 11(4.06) | 36.00 | 2(0.74) | 5.56 | |
Others | 13(4.80) | 37.10 | 2(0.74) | 5.40 | |
Baseline WHO stage | I & II | 34(12.55) | 114.25 | 3(1.11) | 2.63 |
III & IV | 237(87.45) | 1047.00 | 35(12.9) | 3.34 | |
Baseline immunity status | Non-significant/Mild | 87(32.10) | 337.83 | 8(2.95) | 2.37 |
Advanced/ severe | 184(67.90) | 823.42 | 30(11.07) | 3.64 | |
Initial ART regiment based on NRTIs | ABC-based | 10(3.69) | 20.17 | 5(1.85) | 24.81 |
AZT-based | 185(68.27) | 828.33 | 20(7.38) | 2.40 | |
D4T-based | 67(24.72) | 298.17 | 12(4.43) | 4.00 | |
TDF-based | 9(3.32) | 20.99 | 1(0.37) | 4.81 | |
Treatment failure | Yes | 28(10.33) | 149.58 | 5(1.85) | 3.34 |
No | 243(89.67) | 1018.10 | 33(12.18) | 3.24 | |
Clinical failure | Yes | 5(1.85) | 12.67 | 3(1.11) | 23.70 |
No | 266(98.15) | 1155.00 | 35(12.92) | 3.00 | |
Isoniazid | Yes | 97(35.79) | 542.00 | 6(2.21) | 1.11 |
No | 174(64.21) | 625.66 | 32(11.81) | 5.11 | |
Hemoglobin g/dl | <10 | 48(17.71) | 167.58 | 14(5.17) | 8.41 |
> = 10 | 223(82.29) | 1000.10 | 24(8.86) | 2.40 | |
CPT | Yes | 236(87.08) | 1079.58 | 28(10.33) | 2.60 |
No | 35(12.92) | 88.10 | 10(3.69) | 11.40 | |
Adherence | Good | 231(85.24) | 1037.92 | 23(8.49) | 2.22 |
Fair/poor | 40(14.76) | 123.33 | 15(5.54) | 12.20 | |
Site of TB | PTB | 186(68.63) | 801.67 | 13(4.80) | 1.62 |
EPTB | 85(31.37) | 365.999 | 25(9.23) | 6.83 | |
Follow-up years | <1 | 44(16.24) | 15.33 | 23(8.49) | 150.00 |
1–5 | 116(42.8) | 345.92 | 9(3.32) | 2.60 | |
>5 | 111(40.96) | 800.00 | 6(2.21) | 0.75 |