Table 4. Predictors of time to death of TB/HIV co-infected children at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, from February 2005 to March 2017 (n = 271).
| Characteristics | Death | Censored | CHR(95%CI) | AHR(95%CI) | |
|---|---|---|---|---|---|
| Age | <1year | 5 | 6 | 1.00 | 1.00 |
| 1–5 years | 8 | 69 | 0.25 (0.08–0.77)* | 0.3(0.09–0.98)** | |
| 5–10 | 19 | 106 | 0.37(0.14–1.00) | 0.7(0.22–2.3) | |
| 10–14 | 6 | 52 | 0.29(0.09–0.96) | 0.33(0.084–1.33) | |
| Mother HIV status | Positive | 22 | 160 | 1.00 | 1.00 |
| Negative/Unknown | 16 | 73 | 1.77(0.93–3.37) | 1.14(0.26–5) | |
| Address | Urban | 28 | 191 | 1.00 | 1.00 |
| Rural | 10 | 42 | 1.99(0.96–4.11) | 1.58(0.696–3.6) | |
| HIV status of caregiver | Positive | 22 | 154 | 1.00 | 1.00 |
| Negative /Unknown | 16 | 79 | 1.57(0.82–2.997) | 1.69(0.38–7.5) | |
| Immunity status at TB diagnosis | N.S & mild | 8 | 86 | 1.00 | 1.00 |
| Advanced IS | 7 | 59 | 1.17(0.42–3.23)* | 1.3(0.44–3.94) | |
| Sever IS | 23 | 88 | 2.32(1.04–5.199)* | 2.45(0.97–6.2)** | |
| Anemia status at TB diagnosis | Anemic | 14 | 34 | 3.1(1.6–6)* | 2.6(1.24–5.3)** |
| Non-anemic | 24 | 199 | 1.00 | 1.00 | |
| CPT | Yes | 28 | 208 | 1.00 | 1.00 |
| No | 10 | 25 | 3.51(1.68–7.31)* | 4.1(1.76–9.7)** | |
| IPT | Yes | 6 | 91 | 1.00 | 1.00 |
| No | 32 | 142 | 3.87(1.6–9.28)* | 2.95(1.16–7.45)** | |
| Site of TB | PTB | 13 | 173 | ||
| EPTB | 25 | 60 | 4.43(2.26–8.67)* | 2.43(1.1–5.3)** | |
| Adherence | Good | 23 | 208 | 1.00 | 1.00 |
| Fair/poor | 15 | 25 | 4.86(2.5–9.3)* | 3.57(1.7–7.5)** | |
| Time of TB occurrence | Pre ART | 25 | 181 | 1.00 | 1.00 |
| ART | 13 | 52 | 1.68(0.86–3.29) | 1.46(0.68–3.15) | |
N.S = non-significant, I.S = immunosuppression.
* = variables significant in the baviriable at p-value less than 0.05 at 95%CI.
** = variables significant in multivariable at p-value less than 0.05 at 95%CI. Anemic: <10 mg/dl; non-anemic: ≥10 mg/dl.