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. 2018 Apr 9;11(4):dmm031542. doi: 10.1242/dmm.031542

Fig. 4.

Fig. 4.

Aortic dilatation and elastic fiber degradation in FBN1 Het rabbits. (A) Aortic dilatation and decrease of elasticity in the ascending aorta (arrows), and the aortic arch of FBN1 Het rabbits. (B) Aortic dilatation in the abdominal aorta of FBN1 Het rabbits. (C) Weigert stain showing fracture and age-related decrease in elastic fibers (arrows) in the thoracic aorta in FBN1 Het rabbits from 2 to 4 months of age. (D) Statistical analysis showing a decrease in elastic fibers in the thoracic aorta in FBN1 Het rabbits at 2 and 4 months of age. (E) Weigert stain showing age-related decrease in elastic fibers (arrows) in the abdominal aorta in FBN1 Het rabbits from 2 to 4 months of age. (F) Statistical analysis showing decrease in elastic fibers in the abdominal aorta in FBN1 Het rabbits at 2 and 4 months of age. Data are presented as mean±s.e.m. and analyzed using Student's t-tests with GraphPad Prism software 6.0. *P<0.05. n=6. Scale bars: 50 μm.