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| Construct | N | Overall Kd (μM) | Overall ΔH
(kcal/mol) |
Overall TΔS (kcal/mol) |
Overall ΔG (kcal/mol) |
|---|---|---|---|---|---|
| hLBD | 11.2 | 0.9 ± 0.1 | −10.6 ± 0.5 | −2.4 ± 0.6 | −8.2 ± 0.4 |
| AAA8-11 | 6.7 | 0.7 ± 0.1 | −10.4 ± 0.5 | −2.0 ± 0.6 | −8.4 ± 0.4 |
| AAA1-4 | 6.6 | 2.7 ± 0.1 | −12.6 ± 0.6 | −5.0 ± 0.7 | −7.6 ± 0.4 |
| AAA5-11 | 4.2 | 1.5 ± 0.1 | −9.2 ± 0.5 | −1.3 ± 0.6 | −7.9 ± 0.4 |
| AAA1-4, 8–11 | 2.5 | 4.4 ± 0.2 | −12.2 ± 0.6 | −4.9 ± 0.7 | −7.3 ± 0.4 |
