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Sessions to reach acquisition criterion for saccharin and METH self-administration. Individual plots of number of sessions to acquisition criterion for (A) 0.1% saccharin (n = 11-14/group), (B) 0.02 mg/kg/inf METH (n = 7-11/group), (C) 0.05 mg/kg/inf METH (n = 9-16/group), and (D) 0.08 mg/kg/inf METH (n = 9-17/group). The horizontal line within each group indicates the group mean. #p< 0.05 males vs. females; * p< 0.05 adolescent-onset vs. adult-onset.
