Number of reinforced nosepoke responses and reinforcers earned across 15 days of acquisition for (A,B) 0.1% saccharin, (C,D) 0.05 mg/kg/inf METH, and (E,F) 0.08 mg/kg/inf METH. @@p< 0.01, @@@p< 0.001 acquired vs. not acquired for sessions 8-15; ** p< 0.01 adolescent- vs. adult-onset for sessions 8-15; ##p< 0.01 females vs. males for sessions 12-14; * p< 0.05, ** p< 0.01, adolescent- vs. adult-onset;#p< 0.05 females vs. males 3-15.