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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Drug Discov Today. 2018 Jan 9;23(3):661–672. doi: 10.1016/j.drudis.2018.01.018

Table 1.

Therapeutic chemical–disease pairs

Number of diseases Number of chemicals % Chemicals
1 13 972 39.27
2 6657 18.71
5 6605 18.56
10 3119 8.77
20 1980 5.56
30 804 2.26
40 513 1.44
50 300 0.84
60 245 0.69
70 196 0.55
80 151 0.42
90 111 0.31
100 104 0.29
110 93 0.26
120 58 0.16
130 54 0.15
140 58 0.16
150 44 0.12
160 44 0.12
170 33 0.09
180 29 0.08
190 24 0.07
200 26 0.07
210 30 0.08
220 27 0.08
230 32 0.09
240 16 0.04
250 15 0.04
300 51 0.14
>300 189 0.53
Total 35 580 100.00

Over 13 000 chemicals have been tested on only one disease whereas 189 chemicals(the most highly repurposed chemicals according to the definition used here) have been tested for >300 diseases each.