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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Am J Med. 2018 Jan 31;131(6):669–675. doi: 10.1016/j.amjmed.2018.01.011

Table 4.

Multivariate logistic regression for medical diagnoses associated with active hepatitis C.

Diagnosis Univariate OR for HCV+ vs. HCV− Multivariate logistic regression

HCV+ vs. HCV− Current smoker vs. Current non-smoker

ORadj 95% CI ORadj 95% CI

Emphysema* 2.60 2.14 0.92--5.01 7.81 5.40—11.3
Hypertension 1.64 1.65 1.20—2.27 1.13 1.01—1.27
Stroke 1.79 1.80 0.82–3.94 2.33 1.90—2.85
Current depression§ 4.21 2.47 1.69—3.60 2.63 2.28—3.05
Current excessive alcohol|| 2.14 1.12 0.69—1.81 2.14 1.81—2.54

Note: HCV− =without active hepatitis C infection, HCV+=with active hepatitis C infection, OR=odds ratio, ORadj=adjusted odds ratio, CI=confidence intervals

*

Older age and ethnicity/race were also associated with emphysema.

Older age and ethnicity/race were also associated with hypertension.

Older age and ethnicity/race were also associated with stroke.

§

Older age, ethnicity/race, history of use of cocaine, heroin, or methamphetamine, and female gender were also associated with current depression.

||

Younger age, ethnicity/race, history of use of cocaine, heroin, or methamphetamine and male gender were also associated with excessive alcohol use.

Ethnicity/race associated with the highest rates of the specific medical diagnoses were: White for emphysema and excessive alcohol use, Black for hypertension and stroke, and Hispanic (not including Mexican-American) for current depression.