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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Arch Toxicol. 2018 Apr 6;92(5):1767–1783. doi: 10.1007/s00204-018-2185-0

Figure 3. In silico studies demonstrate possible interaction between lipid raft proteins and NLRP10/12.

Figure 3

Protein-protein docking results showing probable interaction between (A) NLRP10 (Green, top left) and Flotillin-1 (Yellow; top left); NLRP10 (Blue, top right) and Caveolin-1 (Red, top right); NLRP10 (Green, bottom left) and Flotillin-2(Blue, bottom left); and NLRP10 (Green, bottom right) and Caveolin-2 (Cyan, bottom right) and (ii) NLRP12 (Orange, top left) and Flotillin-1 (Yellow, top left); NLRP12 (Orange, top right) and Caveolin-1 (Blue, top right); NLRP12 (Blue, bottom left) and Flotillin-2 (Orange, bottom left) and NLRP12 (Orange, bottom right) and Caveolin-2 (Cyan, bottom right), where N10:NLRP10; N12:NLRP12; Cav1:Caveolin-1; Cav2: Caveolin-2; Flot1:Flotillin-1; Flot2: Flotillin-2.