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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Arch Toxicol. 2018 Apr 6;92(5):1767–1783. doi: 10.1007/s00204-018-2185-0

Figure 4. CSE-challenge induces recruitment of NLRP10 and 12 to the lipid rafts and leads to interaction between NLRP12 and Caveolin-1 in A549 cells.

Figure 4

Immunofluorescence results demonstrating recruitment of (A) NLRP10 (Green) and (B) NLRP12 (Green) in the lipid rafts entities (red, shown by labeling GM-1, lipid raft marker), (C) Sub-cellular proximity between NLRP12 and lipid raft protein, and (D) Co-immunoprecipitation of caveolin-1 (lipid raft protein) with the help of anti-NLRP12 antibody following 6-hr CSE challenge in A549 cells.(n=3-4/group). Results are a representation of three independent experiments. Here, No Ab: No Antibody Control and IgG: anti immunoglobulin G control.