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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Arch Toxicol. 2018 Apr 6;92(5):1767–1783. doi: 10.1007/s00204-018-2185-0

Figure 5. CSE-challenge demonstrates cellular co-localization of NLRP10 and NLRP12.

Figure 5

(A) In silico docking results showing probable interactions between NLRP10 (green) and NLRP12 (orange). (B) Immunofluorescence results demonstrating co-localization of NLRP10 (Green) and NLRP12 (red) following 6-hr CSE challenge in THP-1 cells. (n=3-4/group); and (C) Sub-cellular proximity between NLRP10 and NLRP12 as observed by Proximity Ligation Assay following 6-hr CSE challenge in A549 cells. (n=3-4/group). Results are a representation of three independent experiments.