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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Arch Toxicol. 2018 Apr 6;92(5):1767–1783. doi: 10.1007/s00204-018-2185-0

Table 1.

List of interacting amino acids from in silico results.

Interacting amino acids
S. No. NLRP12 amino acid Caveolin-1 Amino acids
1 Arg98 Thr78
2 Thr100 Glu76
3 Val97 Asn173
4 Asp95 Arg171
5 Glu94 Ser168
6 Leu96 Gly 164, Arg171
7 Glu102 Asn169
8 Glu89 Ser88
9 Leu87, Arg90 Glu177
10 Gln92, Trp88 Gln 175
11 Glu89, Arg90 Ile178
Interacting amino acids
S. No. NLRP10 amino acid Caveolin-1 Amino acids
1 None None
Interacting amino acids
S. No. NLRP10 amino acid Caveolin-2 Amino acids
1 Gly1 Val56, Phe104
2 Met5 Asp55
3 Ala8 Phe118
4 Lys10 Ser160, Leu115
5 Asn102 Lys7
6 Met83 Asn6
7 Arg101 Asp138
8 Tyr100 Val139, Asp138
9 Leu97 Val136
10 Leu92 Trp133
11 Asn87 Leu25, Tyr27
12 Ser20 Leu123
13 Trp17 Val125
14 Asp90 Phe91, Leu92
Interacting amino acids
S. No. NLRP12 amino acid Caveolin-2 Amino acids
1 Asn39 His48
2 Asn39, Leu40 Ile71
3 Asn26 Asp17
4 Gly91 Ser18
5 Gly92 Asp17
6 Cys13 Ala97
7 Val25, Phe30 Thr62
8 Thr64 Leu144, Val148
9 Ile63 Ala105, Thr106
10 Arg73 Leu88
11 Asn70 Thr89
12 Asn42 Phe118
Interacting amino acids
S. No. NLRP10 amino acid FlotiHin-1 Amino acids
1 Ser 93 Arg 124
2 Ala 2 Ser 64
3 Asp 99 Gln 125, Leu 151, Thr 150
4 Glu 102 Lys126
5 Met 3 His 155
Interacting amino acids
S. No. NLRP12 amino acid FlotiHin-1 Amino acids
1 Arg-90 His-59, Thr-116,
2 Arg-81 Asp-159
3 Trp-88 Asp-156
4 Leu-62 Asp-153
5 Thr-64 Asn-49
Interacting amino acids
S. No. NLRP10 amino acid Flotillin-2 Amino acids
1 Glu 102 Gln 80
2 Ser 93 Arg 78
3 Gly 1 Tyr 109
4 Ala 2 Lys 111
5 His 98 Ile 105
6 Asp 99 Thr104
Interacting amino acids
S. No. NLRP12 amino acid Flotillin-2 Amino acids
1 Ala 7 Gln 80
2 Leu 22 Arg 63
3 Glu 94 G119
4 Glu 69 Arg 78
5 Arg 90 Glu 14, G15
6 Lys 52 Gln 48
7 Arg 93 Glu 72
8 Thr 78 Lys 111
9 Leu 61 Thr 21
10 Arg 84 Asp 9
11 Trp 88 Asp 110
12 Tyr 18 Leu 69
13 Arg 5 Gln 73, Asp 77