Table 3.
Differentially expressed miRNAs in high-grade dysplastic nodule vs healthy patient’s tissue samples (FDR < 0.05).
| microRNA ID | Chromosome | Fold change | FDR |
|---|---|---|---|
| hsa-miR-101-3p | 1 | 266.25 | 1.10E-02 |
| hsa-mir-22 | 17 | 169.91 | 1.30E-10 |
| hsa-mir-16-1 | 13 | 53.70 | 5.87E-03 |
| hsa-miR-192-5p | 11 | 45.02 | 1.43E-04 |
| hsa-mir-19b-2 | X | 34.12 | 1.68E-03 |
| hsa-mir-486-2 | 8 | 25.83 | 1.76E-04 |
| hsa-mir-130a | 11 | 24.80 | 4.06E-02 |
| hsa-mir-186 | 1 | 23.55 | 2.97E-06 |
| hsa-miR-424-5p | X | 20.63 | 1.50E-02 |
| hsa-mir-10b | 2 | 16.15 | 1.11E-02 |
| hsa-mir-181a-1 | 1 | 16.09 | 4.85E-04 |
| hsa-miR-320a | 8 | 13.48 | 2.01E-02 |
| hsa-mir-10a | 17 | 8.93 | 2.30E-02 |
| hsa-mir-191 | 3 | 8.80 | 2.81E-02 |
| hsa-mir-92a-1 | 13 | 8.19 | 1.46E-02 |
| hsa-miR-127-3p | 14 | 4.94 | 8.02E-03 |
| hsa-mir-193b | 16 | 4.90 | 1.09E-02 |
| hsa-mir-100 | 11 | 4.11 | 3.72E-03 |
| hsa-mir-125b-2 | 21 | −2.90 | 4.18E-02 |
| hsa-mir-106b | 7 | −3.01 | 4.27E-02 |
| hsa-miR-99b-5p | 19 | −3.02 | 2.47E-02 |
| hsa-mir-200b | 1 | −3.81 | 2.62E-02 |
| hsa-mir-140 | 16 | −3.91 | 1.53E-02 |
| hsa-miR-148b-3p | 12 | −3.99 | 2.34E-02 |
| hsa-miR-126-3p | 9 | −4.34 | 1.67E-02 |
| hsa-mir-3591 | 18 | −4.43 | 1.09E-02 |
| hsa-miR-100-5p | 11 | −4.74 | 1.48E-03 |
| hsa-mir-3607 | 5 | −5.39 | 1.35E-02 |
| hsa-miR-423-3p | 17 | −6.19 | 3.76E-03 |
| hsa-mir-101-2 | 9 | −6.49 | 1.53E-02 |
| hsa-miR-93-5p | 7 | −6.63 | 2.12E-03 |
| hsa-let-7a-5p | 11 | −6.99 | 1.31E-02 |
| hsa-miR-24-3p | 19 | −7.33 | 5.92E-03 |
| hsa-mir-199a-2 | 1 | −7.90 | 1.40E-03 |
| hsa-miR-450a-5p | X | −10.52 | 3.21E-02 |
| hsa-miR-374a-5p | X | −13.20 | 1.31E-02 |
| hsa-miR-99a-5p | 21 | −13.46 | 2.70E-05 |
| hsa-mir-27b | 9 | −14.75 | 4.93E-04 |
| hsa-miR-152-3p | 17 | −14.77 | 1.82E-02 |
| hsa-miR-125b-5p | 11 | −15.62 | 6.66E-03 |
| hsa-miR-128-3p | 2 | −16.39 | 2.13E-02 |
| hsa-miR-210-3p | 11 | −16.54 | 1.43E-04 |
| hsa-mir-424 | X | −21.44 | 1.78E-02 |
| hsa-let-7b-5p | 22 | −21.90 | 1.81E-02 |
| hsa-miR-200a-3p | 1 | −24.56 | 1.34E-02 |
| hsa-miR-532-5p | X | −27.50 | 1.64E-04 |
| hsa-mir-103a-2 | 20 | −30.41 | 1.35E-02 |
| hsa-miR-451a | 17 | −35.59 | 1.48E-03 |
| hsa-let-7d-5p | 9 | −35.82 | 5.12E-03 |
| hsa-miR-185-5p | 22 | −70.25 | 3.66E-07 |
| hsa-miR-378c | 10 | −76.83 | 2.87E-05 |
| hsa-let-7g-5p | 3 | −237.19 | 1.48E-03 |
| hsa-miR-122-5p | 18 | −243.58 | 4.71E-07 |
| hsa-miR-30c-5p | 1 | −298.01 | 1.10E-04 |
| hsa-let-7c-5p | 21 | −364.58 | 3.61E-05 |
| hsa-miR-22-3p | 17 | −1000000.00 | 1.03E-16 |
| hsa-let-7f-5p | 9 | −1000000.00 | 1.03E-16 |
| hsa-miR-26b-5p | 2 | −1000000.00 | 1.95E-16 |
| hsa-miR-20a-5p | 13 | −1000000.00 | 3.67E-16 |