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. 2018 May 16;9:1026. doi: 10.3389/fimmu.2018.01026

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Copyright © 2018 Olivares-Morales, De La Fuente, Dubois-Camacho, Parada, Diaz-Jiménez, Torres-Riquelme, Xu, Chamorro-Veloso, Naves, Gonzalez, Quera, Figueroa, Cidlowski, Vidal and Hermoso.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dex and CD2-a modulated gene expression of multiple inflammatory genes. Genes that showed statistically significant differences for any of the three conditions and that affect immune response were selected and grouped into four categories: (1) cytokines, (2) chemokines, (3) TLR signaling, and (4) M1 and M2 markers. The heatmap indicates increased (red/upregulated) or decreased (green/downregulated) expression levels when subjected to each group, compared to control.