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. 2018 May 16;9:1026. doi: 10.3389/fimmu.2018.01026

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Copyright © 2018 Olivares-Morales, De La Fuente, Dubois-Camacho, Parada, Diaz-Jiménez, Torres-Riquelme, Xu, Chamorro-Veloso, Naves, Gonzalez, Quera, Figueroa, Cidlowski, Vidal and Hermoso.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dexamethasone decreases phagocytosis of macrophages against Escherichia coli strains. THP-1 macrophages treated with 100 nM Dex for 24 h were infected with E. coli strains (multiplicity of infection: 10). Amikacin protection assay was performed after 30 min of infection to evaluate phagocytic levels. (A) Absolute intracellular CFU count showing different quantities of phagocytosed strain inhibited by Dex. (B) Normalization to vehicle. Two-way ANOVA and Bonferroni corrections were performed (n = 6; p < 0.05 compared to vehicle).