Table 2.

Top canonical pathways modulated by Dex.

	p-Value	Overlap
Dex vs. control
Role of macrophages, fibroblasts, and endothelial cells in rheumatoid arthritis	1.08E−08	11.8% 35/296
G-protein coupled receptor signaling	1.47E−07	11.7% 30/256
Phagosome formation	3.15E−07	16.5% 18/109
Gq signaling	1.73E−06	13.6% 20/147
Glioma invasiveness signaling	2.11E−06	21.1% 12/57
CD2-a + Dex vs. CD2-a
Role of macrophages, fibroblasts, and endothelial cells in rheumatoid arthritis	7.41E−05	10.8% 32/296
Toll-like receptor signaling	1.02E−04	17.6% 13/74
HMGB1	1.55E−04	14.2% 17/120
NF-kB signaling	2.60E−04	12.1% 21/173
FXR/RXR activation	3.10E−04	13.4% 17/127