Table 1.

Eye movement abnormalities in neurodegenerative disorders.

Disorder	Oculomotor findings
Parkinson’s disease	Increased saccade latency, decreased saccade amplitude, increased anti-saccade error rate (53, 55, 56) Diplopia in up to 20% (58) Convergence insufficiency (57) Increased convergence and divergence latency (60)
SCA3	Ophthalmoplegia, lid retraction, diplopia (74, 77) Strabismus in up to 83% (78) Divergence insufficiency (77)
SCA6	Diplopia in up to 50% (84) Vertical nystagmus, horizontal gaze-evoked nystagmus (85)
Huntington disease	Increased saccade latency, decreased saccade velocity, increased anti-saccade error rate (91–94)
Multiple system atrophy	Blepharospasm, square-wave jerks (97) Rare reports of vergence paresis resulting in diplopia (99)
Progressive supranuclear palsy	Slow vertical saccades, vertical gaze palsy (100) Square-wave jerks (101)
Corticobasal degeneration	Asymmetric saccadic apraxia, increased saccade latency, increased anti-saccade error (106, 107)
Dementia with Lewy bodies	Increased saccadic latency, increased anti-saccade error rate (110, 111) Case reports of supranuclear gaze palsy (112)