Table 3.
Principal B cell subsets with innate-like functions.
B cell subset | B-1a cells | Marginal zone B cells | T-bet positive B cells | Innate response activator B cells | Natural killer-like B cells | IL-17-producing B cells | Human self-reactive VH4-34-expressing B cells |
---|---|---|---|---|---|---|---|
Associated pathology | Type-1 diabetes (T1D), rheumatoid arthritis (RA) | Atherosclerosis, T1D | RA, scleroderma, systemic lupus erythematous | Under investigation | Under investigation | Under investigation | Under investigation |