Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 16;9:1018. doi: 10.3389/fmicb.2018.01018

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Rabelo, Souza, Salomão, Oliveira, Sentinelli, Lacerda, Saraquino, Rosman, Basílio-de-Oliveira, Carvalho and Paes.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Histopathological analysis of the fetal organs. (A–J) All tissues were stained with H. E. (A) Brain of a non-ZIKV case presenting normal aspect: cerebral cortex (CC) and neurons (Ne). (B) Brain of a ZIKV infected fetus, presenting areas of degenerated nerve fibers (DF). (C) Lung section of a control fetus showing normal bronchioles (BC). (D) Injuries in fetal lung infected by ZIKV: disorganized bronchioles (DBC) with loss of cylindrical appearance, focal areas of hyaline membrane (HM), diffuse mononuclear infiltrates (Inf) and peeled cells of respiratory epithelium (PC). (E) Skin dermis (DM) of a non-ZIKV case presenting normal aspect, epidermis (Epi), blood vessel (BV). (F) Skin dermis of a ZIKV infected fetus, with perivascular and mononuclear infiltrate (PInf and Inf) and areas of edema (E). (G) Kidney of a non-ZIKV case presenting normal aspect, with normal glomerulus (GR) and proximal contorted tubules (PCT). (H) Kidney sections showing injuries, including: disorganized renal glomerulus (GR), tubular disarrangement and inflammatory infiltrate (Inf). (I) Section of a control liver, with normal bile duct (BD) and portal vein (PV). (J) Liver of a ZIKV infected fetus, presenting dilatation of sinusoidal capillaries (SC), hepatic parenchymal disorganization and Kupffer cells (KC).