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R406 does not result in permanent macrophage response defects to fungal stimuli as measured by reactive oxygen species (ROS) production. Plated macrophages were treated with R406 for 2 h, and then washed to remove the inhibitor. ROS production measured by lucigenin after addition of heat-killed Candida. Arbitrary light unites (AU) represents total luminescence corresponding with ROS production. *p ≤ 0.05, ****p ≤ 0.0001. Data represent a minimum of three independent experiments.
