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. 2018 May 22;4:12. doi: 10.1038/s41522-018-0055-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Functional classification of proteins differentially regulated in the multispecies oral biofilms containing A. actinomycetemcomitans strain D7S and D7S hns, respectively. All up- or downregulated bacterial protein functions in the D7S relative to the D7S hns biofilms were annotated by enrichment of Gene Ontology (GO) terms, and displayed as proportions (%) of the total numbers of regulated (up/down) GO terms. Indicated is the numbers of GO terms for biological process, cellular component, and molecular function, respectively. Sub-domains with their GO proportion less than 2% were classified as “other”