Table 1.

The top 10 of the results of lncRNAs with an up or downregulation in expression in the hepatic damage models compared with control

Gene symbol	Seq name	Fold change	P value	Reg.	RNA length (b)	Model (raw)	Control (raw)	Model (normalized)	Control (normalized)
Rpph1	ENSMUST00000175096	367.75	<0.001	Up	319	10,878.23	29.30	13.43	4.90
Vaultrc5	ENSMUST00000083211	232.90	<0.001	Up	143	26,870.34	133.39	14.85	6.98
Trp73	ENSMUST00000083211	90.27	<0.001	Up	1861	3510.71	51.71	12.19	5.69
Rprl2	NR_004439	83.38	<0.001	Up	238	837.63	7.24	9.35	2.97
Jarid2	2_00008059	82.43	<0.001	Up	327	10,653.61	127.06	13.25	6.89
Rmrp	ENSMUST00000157463	66.49	<0.001	Up	271	15,290.54	262.26	13.94	7.89
AK155692	uc029sug.1	61.14	<0.001	Up	532	13,804.82	229.16	13.63	7.70
M34473	uc009cfw.1	59.62	<0.001	Up	796	28,404.87	537.14	14.74	8.84
H2-Eb1	uc029thf.1	53.28	<0.001	Up	1416	2185.64	43.92	11.20	5.46
Gm25403	ENSMUST00000082971	47.59	<0.001	Up	143	4705.24	86.45	11.96	6.39
AK019750	AK019750	212.43	<0.001	Down	436	11.91	2207.26	2.95	10.69
AK131807	AK131807	211.89	<0.001	Down	879	208.64	16,792.93	5.73	13.46
Mup-ps15	ENSMUST00000121741	209.91	<0.001	Down	539	51.40	7254.99	4.56	12.27
AK020603	AK020603	204.43	<0.001	Down	431	61.37	7544.16	4.65	12.33
Mup-ps12	ENSMUST00000126217	202.67	<0.001	Down	549	317.35	56,757.47	7.56	15.22
humanlincRNA2050	AI507368	195.38	<0.001	Down	458	175.87	13,927.47	5.57	13.18
Gm14450	ENSMUST00000119984	154.47	<0.001	Down	240	183.91	17,550.66	6.25	13.52
Mup-ps17	ENSMUST00000120723	151.37	<0.001	Down	218	57.77	6435.20	4.87	12.11
Mup-ps21	ENSMUST00000119998	142.45	<0.001	Down	448	837.47	75,777.63	8.48	15.64
Mup-ps4	ENSMUST00000169784	139.43	<0.001	Down	474	76.74	8552.54	5.38	12.50

To identify differentially expressed lncRNAs, we performed a fold change (FC) filtering between CCl₄ and control groups. The cutoff standard is the top 1% FC arranged from high to low. Seq name—lncRNA name. Absolute fold change—absolute fold change between the two groups. Reg—regulation in the hepatic damage model compared to control; “Up” indicates upregulated lncRNA in hepatic damage model compared with control; “Down” indicates downregulated one in hepatic damage model compared with control. Model-normal (raw)—raw intensities of each sample. Model-normal (normalized)—normalized intensities of each sample (log2-transformed). The list only shows the top 10 of the results of lncRNAs with an up or downregulation in expression in the hepatic damage models vs. control