Fig. 5.

Structural and nuclear pore complex proteins: young (a), elderly (b) and exercised (c) animal immunostaining for structural protein LaminB1. Young (e), elderly (f) and exercised (g) animal immunostaining for nuclear pore complex protein, nucleoporin 93. Young (i), elderly (j) and exercised (k) animal immunostaining for nuclear pore complex protein, nucleoporin 98. For each protein and group, ×40 magnification images are in the inset. Sedentary ageing elicited significant decline in immunostaining of LaminB1 (d), nucleoporin 93 (h) and nucleoporin 98 (l) compared to both young and exercised animals. Data expressed as mean ± SEM *p < 0.05. Young n = 5, elderly n = 5 and exercised n = 5; 50 nuclei per animal (scale 20 μm)