Table 2.
Baseline characteristics by antidepressant prescribing and weight gain. Values are frequencies except unless stated otherwise
Characteristics | No antidepressant | Antidepressant | |||||
---|---|---|---|---|---|---|---|
Person years | ≥5% weight gain | Incidence/100 person years | Person years | ≥5% weight gain | Incidence/100 person years | ||
Total | 1 454 909 | 118 462 | 8.1 | 381 543 | 42 839 | 11.2 | |
Men | 728 208 | 54 494 | 7.5 | 129 862 | 13 398 | 10.3 | |
Women | 726 701 | 63 968 | 8.8 | 251 680 | 29 441 | 11.7 | |
Age group (years): | |||||||
20-29 | 101 633 | 11 163 | 11.0 | 19 792 | 2993 | 15.1 | |
30-39 | 163 285 | 15 704 | 9.6 | 44 017 | 6048 | 13.7 | |
40-49 | 252 218 | 22 289 | 8.8 | 79 302 | 9988 | 12.6 | |
50-59 | 290 131 | 23 880 | 8.2 | 88 597 | 10 109 | 11.4 | |
60-69 | 314 516 | 24 403 | 7.8 | 78 431 | 7957 | 10.1 | |
70-79 | 229 011 | 14 976 | 6.5 | 48 182 | 4065 | 8.4 | |
≥80 | 104 116 | 6047 | 5.8 | 23 221 | 1679 | 7.2 | |
BMI category (kg/m2): | |||||||
14.0-18.4 | 4959 | 101 | 2.0 | 1571 | 40 | 2.5 | |
18.5-24.9 | 250 546 | 12 507 | 5.0 | 47 916 | 3269 | 6.8 | |
25.0-29.9 | 329 117 | 23 307 | 7.1 | 67 697 | 6413 | 9.5 | |
30.0-34.9 | 308 812 | 23 573 | 7.6 | 76 823 | 7575 | 9.9 | |
35.0-39.9 | 264 974 | 22 320 | 8.4 | 76 047 | 8172 | 10.7 | |
40.0-44.9 | 176 339 | 18 110 | 10.3 | 59 696 | 7731 | 14.0 | |
≥45.0 | 120 163 | 18 544 | 15.4 | 51 793 | 9639 | 18.6 | |
Comorbidity: | |||||||
Coronary heart disease | 172 445 | 13 471 | 7.8 | 49 570 | 4989 | 10.1 | |
Diabetes | 314 672 | 26 708 | 8.5 | 100 183 | 10 704 | 10.7 | |
Stroke | 37 882 | 3041 | 8.0 | 15 115 | 1555 | 10.3 | |
Cancer | 112 346 | 8048 | 7.2 | 30 356 | 2871 | 9.5 | |
Depression recorded | 7215 | 737 | 10.2 | 66 660 | 7740 | 11.6 | |
Coprescribing: | |||||||
Antiepileptic | 24 657 | 2360 | 9.6 | 16 240 | 1993 | 12.3 | |
Antipsychotic | 14 676 | 1740 | 11.9 | 24 815 | 3591 | 14.5 | |
Index of multiple deprivation fifth: | |||||||
1st (least deprived) | 237 325 | 17 874 | 7.5 | 53 146 | 5735 | 10.8 | |
2nd | 280 343 | 22 523 | 8.0 | 69 182 | 7638 | 11.0 | |
3rd | 300 334 | 24 207 | 8.1 | 77 382 | 8503 | 11.0 | |
4th | 324 533 | 26 771 | 8.2 | 88 440 | 10 096 | 11.4 | |
5th (most deprived) | 312 373 | 27 087 | 8.7 | 93 392 | 10 867 | 11.6 | |
Current smoker | 326 618 | 27 992 | 8.6 | 117 164 | 13 796 | 11.8 | |
Diet advice | 403 929 | 48 006 | 11.9 | 114 533 | 18 538 | 16.0 |