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. 2018 May 16;361:k1951. doi: 10.1136/bmj.k1951

Table 2.

Baseline characteristics by antidepressant prescribing and weight gain. Values are frequencies except unless stated otherwise

Characteristics No antidepressant Antidepressant
Person years ≥5% weight gain Incidence/100 person years Person years ≥5% weight gain Incidence/100 person years
Total 1 454 909 118 462 8.1 381 543 42 839 11.2
Men 728 208 54 494 7.5 129 862 13 398 10.3
Women 726 701 63 968 8.8 251 680 29 441 11.7
Age group (years):
 20-29 101 633 11 163 11.0 19 792 2993 15.1
 30-39 163 285 15 704 9.6 44 017 6048 13.7
 40-49 252 218 22 289 8.8 79 302 9988 12.6
 50-59 290 131 23 880 8.2 88 597 10 109 11.4
 60-69 314 516 24 403 7.8 78 431 7957 10.1
 70-79 229 011 14 976 6.5 48 182 4065 8.4
 ≥80 104 116 6047 5.8 23 221 1679 7.2
BMI category (kg/m2):
 14.0-18.4 4959 101 2.0 1571 40 2.5
 18.5-24.9 250 546 12 507 5.0 47 916 3269 6.8
 25.0-29.9 329 117 23 307 7.1 67 697 6413 9.5
 30.0-34.9 308 812 23 573 7.6 76 823 7575 9.9
 35.0-39.9 264 974 22 320 8.4 76 047 8172 10.7
 40.0-44.9 176 339 18 110 10.3 59 696 7731 14.0
 ≥45.0 120 163 18 544 15.4 51 793 9639 18.6
Comorbidity:
 Coronary heart disease 172 445 13 471 7.8 49 570 4989 10.1
 Diabetes 314 672 26 708 8.5 100 183 10 704 10.7
 Stroke 37 882 3041 8.0 15 115 1555 10.3
 Cancer 112 346 8048 7.2 30 356 2871 9.5
 Depression recorded 7215 737 10.2 66 660 7740 11.6
Coprescribing:
 Antiepileptic 24 657 2360 9.6 16 240 1993 12.3
 Antipsychotic 14 676 1740 11.9 24 815 3591 14.5
Index of multiple deprivation fifth:
 1st (least deprived) 237 325 17 874 7.5 53 146 5735 10.8
 2nd 280 343 22 523 8.0 69 182 7638 11.0
 3rd 300 334 24 207 8.1 77 382 8503 11.0
 4th 324 533 26 771 8.2 88 440 10 096 11.4
 5th (most deprived) 312 373 27 087 8.7 93 392 10 867 11.6
Current smoker 326 618 27 992 8.6 117 164 13 796 11.8
Diet advice 403 929 48 006 11.9 114 533 18 538 16.0