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Histology (a) and immunohistochemistry (b–d) of a resected epipapillary membrane tissue in case 4. (a) Light micrograph demonstrating marked hyalinization. Spindle-shaped stromal cells were intermingled in the section (hematoxylin-eosin). (b) Immunochemistry for cytokeratin. Immunoreactivity was not observed. (c) Immunoreactivity for S100 was detected in the membrane (arrows). (d) Immunoreactivity for GFAP was strongly detected in the membrane (arrows).
