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DETECT algorithm. ACA: anti-centromere antibody; DLCO: diffusing capacity of carbon monoxide; FVC: forced vital capacity; NT-proBNP: N-terminal probrain natriuretic peptide; TR: tricuspid regurgitation (cited and modified from “Evidence-Based Detection of Pulmonary Arterial Hypertension in Systemic Sclerosis: The DETECT Study” by Coghlan JG, et al. Ann Rheum Dis 2014; 73: 1340-9).
