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. 2018 May 8;2018:1838921. doi: 10.1155/2018/1838921

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Copyright © 2018 Yazmin M. Flores-Martinez et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Nitrosative and oxidative stress in the substantia nigra after LPS local injection. (a) Nitrosative stress was evaluated through the levels of nitrites. (b) Oxidative stress (lipid peroxidation) was evaluated through the levels of malondialdehyde (MDA) + 4-hydroxyalkenals (4-HAE). Ut = untreated control rats. Mock = rats injected with the vehicle (2 μL of endotoxin-free physiological saline solution) in the left substantia nigra. The values represent the mean ± SD from 5 rats for each time and each experimental condition. ^∗ P < 0.001 when compared with the untreated control group. ^† P < 0.001 when compared with the respective mock group. Repeated-measures one-way ANOVA and Bonferroni post hoc test.