FIG 6.

Effects of mating type and white-opaque phenotype on the capacity of C. albicans to damage oral epithelial cells. Oral epithelial cells were infected with the indicated C. albicans strains for 7 h, after which the extent of host cell damage was determined by ⁵¹Cr release assay. (A) Damage by strain SC5314 and white and opaque cells of the a/a strain 05GH and the α/α strain WOmCh. (B) Damage by strains SC5314, SC5314a/−, and SC5314−/α. Results are means ± SD from three experiments, each performed in triplicate. Statistical significance was determined using ANOVA multiple comparison with Bonferroni correction. ****, P < 0.0001. NS, not significant.