FIG 2.

Nasal mupirocin treatment effectively clears pig-tailed macaque nostrils and external sites. (A) The S. aureus load before and after nasal mupirocin (mup) application for each body site (average for the left and right for nostrils, axilla, and palms). Error bars indicate the mean and SEM (n = 24; 6 animals, 4 experiments each). (B) The animals' nostrils were swabbed prior to the first topical application of mupirocin and then weekly for 4 weeks, and the number of non-S. aureus CFU was enumerated. Error bars indicate the mean and SEM. The dotted horizontal lines indicate the limit of S. aureus detection (10 CFU/swab).