FIG 7.

Similar association between the nasal inflammatory peak and the S. aureus carriage duration in pig-tailed macaques and humans. The peak nasal inflammatory response to experimentally inoculated S. aureus was assessed by Luminex measurements of IL-1β and IL-8 in collected nasal secretions. For each of 18 macaque inoculations (A) and 43 human inoculations (B), the occurrence of the peak inflammatory response postinoculation (x axis) was plotted according to the duration of S. aureus carriage (y axis). Error bars indicate the mean and SEM. The triangles in panel A represent animals that were carrying S. aureus nasally on the last day of follow-up (thus, the carriage duration was actually longer).