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Comparison of A8 and E12 epitopes on PTx. Experimentally determined conformational epitopes for A8 (yellow) (A) and E12 (blue) (B) are shown. (C) Rotated views (90°) of the PTx S1 crystal structure (PDB entry 1PRT), with conserved residues indicated for A8 (yellow), E12 (blue), overlapping A8 and E12 (green), and hu1B7 (red) (23, 24).
