Table 1.
Features, instrumentation and acquisition methods of every representative HSI system reported in the current article for brain metabolic and hemodynamic monitoring.
| References | Spectral range (nm) | Number of spectral bands | Spectral resolution (nm) | Acquisition mode | Illumination setup | Detection setup | Metabolism target | Targeted stimulus or condition |
|---|---|---|---|---|---|---|---|---|
| Malonek [87] | 500–700 | — | 1–4 | Linear scanning | White light source | CCD + slit + diffraction grating | Tissue oxygenation | Visual stimulation |
| Devor [89] | 560–610 | 6 | 10 | Spectral scanning | White light source + filter wheel | CCD | Tissue oxygenation | Whisker stimulation |
| Konecky [91] | 484–652 | 38 | 3–8 | Snapshot | White light source | CCD + prism array | Tissue oxygenation | Whisker stimulation |
| Shonat [94] | 504–600 | 12 | 5 | Spectral scanning | White light source | CCD + AOTF | Tissue oxygenation | Hypoxia and hyperoxia |
| Pichette [98] | 481–632 | 16 | ∼15 | Snapshot | White light source | Commercial snapshot camera | Tissue oxygenation | Epileptic spikes |
| Dunn [88], [89], [109] | 560–610, 768 | 7 | 10 | Spectral scanning | White light source + filter wheel + laser | CCD | CMRO2 | Tactile stimulation |
| Jones [110] | 560–610, 768 | 7 | 10 | Spectral scanning | White light source + filter wheel + laser | Two CCDs | CMRO2 | Focal cerebral ischemia |
| Gao [134] | ∼480–600 | 25 | 5.6 | Snapshot | White light source + filters | CCD + image slicer | Fluorescence | Fluorescent phantom model |
| Yin [95] | 450–650 | 9 | 20 | Spectral scanning | White light source | CCD + LCTF | CCO | CSD |
Note. CCD, charge-coupled device; AOTF, acousto-optical tunable filter; CMRO2, cerebral metabolic rate of oxygen; LCTF, liquid crystal tunable filter; CCO, cytochrome-c-oxidase; CSD, cortical spreading depression.