Table 1.
Demographics of patients with Stevens-Johnson syndrome and overlap-toxic epidermal necrolysis.
| SJS, N = 20 | Overlap-TEN, N = 16 | Overall, N = 36 | P value | |
|---|---|---|---|---|
| Male (%) | 8 (40.0) | 8 (50.0) | 16 (44.4) | 0.549 |
|
| ||||
| Age (yr) (mean ± SD) | 8.6 ± 4.2 | 9.9 ± 3.6 | 9.2 ± 4.0 | 0.373 |
|
| ||||
| Underlying diseases, N (%) | 0.623 | |||
| None | 7 (35.0) | 8 (50.0) | 15 (41.6) | |
| Neurological diseases | 6 (30.0) | 6 (37.5) | 12 (33.3) | |
| (seizure, MELAS, GBS) | ||||
| HIV | 2 (10.0) | 1 (6.2) | 3 (8.3) | |
| ESRD | 1 (5.0) | 1 (6.2) | 2 (5.6) | |
| Wilson disease | 2 (10.0) | 0 | 2 (5.6) | |
| SLE | 1 (5.0) | 0 | 1 (2.8) | |
| Cyanotic heart disease | 1 (5.0) | 0 | 1 (2.8) | |
|
| ||||
| Probable causative factors (%) | 0.185 | |||
| Unknown | 4 (20.0) | 2 (12.5) | 6 (16.6) | |
| Infection | 1 (5.0) | 3 (18.8) | 4 (11.1) | |
| Drug | 15 (75.0) | 11 (68.7) | 26 (72.3) | |
| Antiepileptics | 5 (25.0) | 8 (50.0) | 13 (36.1) | |
| Antibiotics | 7 (35.0) | 2 (12.5) | 9 (25.0) | |
| D-penicillamine | 2 (10.0) | 0 | 2 (5.6) | |
| Antivirus | 1 (5.0) | 1 (6.2) | 1 (2.8) | |
| NSAIDs | 0 | 0 | 1 (2.8) | |
MELAS, mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke; GBS, Guillain-Barre syndrome; HIV, human immunodeficiency virus; ESRD, end-stage renal disease; SLE, systemic lupus erythematosus.