Table 2.
Clinical features of patients with Stevens-Johnson syndrome and overlap-toxic epidermal necrolysis.
| SJS, N = 20 | Overlap-TEN, N = 16 | Overall, N = 36 | P value∗ | |
|---|---|---|---|---|
| Prodromal symptoms, N (%) | 15 (75.0) | 11 (68.8) | 26 (72.2) | 0.677 |
| Fever | 14 (70.0) | 11 (68.8) | 25 (69.4) | 0.352 |
| Stinging eye | 4 (20.0) | 4 (25.0) | 8 (22.2) | 0.477 |
| Sore throat | 5 (25.0) | 1 (6.2) | 6 (16.7) | 0.274 |
|
| ||||
| Cutaneous findings at the presentation, N (%) | ||||
| Morbilliform rash | 19 (95.0) | 11 (68.8) | 30 (83.3) | 0.036 |
| Blister | 5 (25.0) | 9 (56.3) | 14 (38.9) | 0.056 |
| Targetoid lesions | 6 (30.0) | 3 (18.8) | 9 (25.0) | 0.439 |
| Purpuric macules | 1 (5.0) | 0 | 1 (2.8) | 0.364 |
|
| ||||
| Mucosal involvement, N (%) | ||||
| Oral | 19 (95.0) | 16 (100.0) | 35 (97.2) | 0.364 |
| Eye | 17 (85.0) | 13 (81.2) | 30 (83.3) | 0.764 |
| Genital | 15 (75.0) | 11 (68.8) | 26 (72.2) | 0.677 |
| Anus | 3 (15.0) | 3 (18.8) | 6 (16.7) | 0.764 |
|
| ||||
| Associated abnormalities | ||||
| GI abnormalities | 9 (45.0) | 9 (56.3) | 18 (50.0) | 0.502 |
| Transaminitis | 9 (45.0) | 9 (56.3) | 18 (50.0) | 0.645 |
| Direct hyperbilirubinemia | 3 (15.0) | 0 | 3 (8.3) | 0.106 |
| Electrolyte abnormalities | 8 (40.0) | 8 (50.0) | 13 (44.4) | 0.568 |
| Hyponatremia | 5 (25.0) | 3 (18.8) | 8 (22.2) | 0.654 |
| Hypokalemia | 3 (15.0) | 4 (25.0) | 7 (19.4) | 0.451 |
| Hypocalcemia, hypophosphatemia | 0 | 1 (6.2) | 1 (2.8) | 0.257 |
| Renal abnormalities | 1 (5.0) | 1 (6.2) | 2 (5.6) | 0.359 |
| Rising creatinine | 1 (5.0) | 0 | 1 (2.8) | 0.364 |
| Rising creatinine and hematuria | 0 | 1 (6.2) | 1 (2.8) | 0.257 |
∗Significant values are shown in bold.