. 2018 May 7;2018:3082526. doi: 10.1155/2018/3082526

Table 1.

Endogenous sister chromatid exchange in sarcoma cell lines.

Cell line	Histological subtype	Passage number	Number of metaphases	Chromosome count, median (range)	Median SCE count		Range
Cell line	Histological subtype	Passage number	Number of metaphases	Chromosome count, median (range)	Observed	^aNormalised
Nontumour/low SCE controls
hTERT-RPE1	Normal retinal epithelium		7	43 (31–48)	8	8	6–13
SOM-196b	Uveal melanoma		11	45 (34–46)	6	6	1–14
Commercially available sarcoma cell lines
U-2 OS	Osteosarcoma		30	71 (64–76)	47	31	17–63
SK-LMS-1	Leiomyosarcoma		10	100 (86–151)	42	18	14–37
SK-UT-1	Uterine leiomyosarcoma		20	44 (32–48)	14	15	8–31
SW-1353	Chondrosarcoma		12	48 (45–53)	17	16	9–20
Primary sarcoma cell lines
Shef-UPS 01	Undifferentiated pleomorphic sarcoma	p69	22	59 (44–67)	13	10	7–18
^bShef-UPS 02	Undifferentiated pleomorphic sarcoma	p15	10	60 (56–60)	23	17	10–27
^bShef-UPS 02	Undifferentiated pleomorphic sarcoma	p30	7	89 (53–114)	24	16	7–30
^bShef-UPS 03	Undifferentiated pleomorphic sarcoma	p17	29	56 (47–60)	23	18	9–33
^bShef-UPS 03	Undifferentiated pleomorphic sarcoma	p33	24	71 (50–126)	23	17	9–32
^bShef-UPS 04	Undifferentiated pleomorphic sarcoma	p3	12	60 (51–65)	20	16	8–25
^bShef-UPS 04	Undifferentiated pleomorphic sarcoma	p8	30	59 (52–69)	20	15	7–30
Shef-DDLPS 01	Dedifferentiated liposarcoma	p70	29	76 (41–97)	22	13	7–21
^b,cShef-DDLPS 02	Dedifferentiated liposarcoma	p12	30	108 (51–154)	35	14	9–25
^b,cShef-DDLPS 02	Dedifferentiated liposarcoma	p23	29	117 (52–151)	33	13	7–26
Shef-LMS 01 w₁	Leiomyosarcoma	p51	25	127 (74–152)	28	10	8–20
Shef-LMS 01 w_s	Leiomyosarcoma	p62	22	118 (80–134)	31	11	7–21
Shef-MFS 02	Myxofibrosarcoma	p2	15	77 (42–105)	24	15	11–26

^aNormalised for 2n karyotype by multiplying observed SCE counts by 46 and then dividing by observed chromosome number. ^bTumour was previously treated with radiotherapy prior to resection. ^cSCE analysis was repeated after further in vitro culture.