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. 2018 May 23;22:133. doi: 10.1186/s13054-018-2055-4

Table 4.

Primary outcome

Variable GDHT group Usual care group Absolute difference (95% CI) p
(n = 64) (n = 64)
Composite endpoint 53 (40–66) 44 (31–57) 9.4 (−7.8 to 25.8) 0.3
 Mortality 14 (7–25) 9 (4–19) 4.7 (−6.9 to 16.4) 0.4
 Stroke 0 (0–6) 2 (0–8) −1.6 (−8.3 to 4.2) 0.9
 AKI 51 (36–61) 39 (27–52) 9.4 (− 7.6 to 25.6) 0.2
 ARDS 5 (2–15) 2 (0–8) 4.7 (−3.1 to 13.5) 0.4
 Acute myocardial infarction 2 (0–8) 5 (0.9–13) −3.1 (− 11.4 to 4.3) 0.6
 Acute heart failure 0 (0–6) 2 (0–8) −1.6 (− 8.3 to 4.2) 0.5
 Mesenteric ischemia 2 (0–8) 0 (0–6) 1.6 (−4.2 to 8.3) 0.9
 Peripheral vascular ischemia 0 (0–6) 3 (0.3–11) − 3.1 (− 10.7 to 3.0) 0.5
 Pulmonary embolism 0 (0–6) 0 (0–6)
 Deep wound infection 3 (0.3–11) 8 (3–17) −4.7 (− 14.2 to 4.1) 0.4
 Reoperation 8 (3–17) 5 (0.9–13) 3.1 (− 6.2 to 12.8) 0.7

Data presented as % (95% CI)

GDT goal-directed hemodynamic therapy, CI confidence interval, AKI acute kidney injury, ARDS acute respiratory distress syndrome