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. 2018 Feb 27;18:599–607. doi: 10.1016/j.nicl.2018.02.027

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Brain states and lobar brain structure. (A) Brain state networks are quantified by calculating the functional connectivity between electrodes based on the pairwise mean-squared coherence (MSC) between recorded activity. (B) No differences are observed in the average connectivity strength of full brain state networks before and after the cognitive intervention. (C) Average connectivity strength of AD and non-AD subnetworks before and after the cognitive intervention. In both cases, the AD subnetwork shows a significantly weaker connectivity than its non-AD counterpart. (D) Percentage of AD subnetwork contained in the frontal (left column), parietal (middle column), and temporal (right column) lobes for trials where the majority of the AD subnetwork is located within the frontal (top row), parietal (middle row), or temporal (bottom row) lobe. No significant differences are observed between spatial relationships in trials where ADs stopped or continued.